CAR T Cell Therapy Treatments
The FDA has approved 6 CAR T cell therapy treatments. These treatments are typically for patients where the cancer is refractory or relapsed after having 1 or more prior treatments. Refractory means the cancer did not respond to the previous treatment. Relapsed means the cancer returned even after prior treatments. New CAR T cell therapy treatments and new ways to use currently approved treatments are being studied in clinical trials.
Important Things to Know About Side Effects:
The CAR T infusion can cause side effects. Some patients experience severe side effects, while others experience mild or no side effects. Patients who start CAR T cell therapy will be told about all the possible side effects they might have. It is very important that patients tell their doctors about any side effects they experience. Most side effects can be managed if they are treated early.
These are the current CAR T cell therapies approved for treatment as of June 2024.
Important Things to Know - All Drugs:
Cytokine Release Syndrome (CRS) may occur. This condition can cause flu-like symptoms, like fever and chills. Other conditions like neurotoxicity, tumor lysis syndrome, cytopenia, and B cell aplasia also may occur. These conditions can cause side effects, and some may be severe. Your healthcare team should discuss all potential side effects with you and your caregiver.
Treatment Type
CAR T Cell Therapy
Drug Name
Who Can Use It?
Children and young adults up to 25 years of age | Approved to treat acute lymphoblastic leukemia (ALL) where:
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Adults | Approved to treat large B cell lymphomas where:
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Drug Name
Who Can Use It
Adults | Approved to treat large B cell lymphoma where:
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Drug Name
Who Can Use It
Adults | Approved to treat mantle cell lymphoma (MCL) where:
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Drug Name
Who Can Use It
Adults | Approved to treat large B cell lymphoma where:
Approved to treat chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) when:
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Drug Name
Who Can Use It
Adults | Approved to treat multiple myeloma where:
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Drug Name
Important Things to Know
Adults | Approved to treat relapsed or refractory multiple myeloma where:
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