Immunotherapy Overview

This booklet helps patients and caregivers understand immunotherapy, a type of cancer treatment that uses the body’s own immune system to find and attack cancer cells. It explains what immunotherapy is, how it works, and the different types that may be used to treat cancer. The booklet also describes how immunotherapy is given, including IV (intravenous) infusions and under-the-skin (subcutaneous) injections, and how these options compare with other cancer treatments.

You will find information about who may benefit from immunotherapy, including how cancer type, biomarkers, overall health, and past treatments can affect whether immunotherapy is an option. The booklet reviews common and less common side effects, what symptoms to watch for, and why early communication with your care team is important. It also includes guidance on treatment costs, clinical trials, and supportive resources to help you and your loved ones cope during treatment.

Most importantly, this booklet emphasizes that you are an active partner in your care. Your values, goals, and daily life matter when making treatment decisions. By learning about immunotherapy and asking questions, you can work with your healthcare team to make informed choices and feel more confident as you move forward in your cancer care.

Key Takeaways:

• Immunotherapy helps the immune system recognize and attack cancer cells in different ways.
• There are several types of immunotherapy, including checkpoint inhibitors, monoclonal antibodies, cell therapy, and treatment vaccines.
• Not every patient benefits from immunotherapy, and factors like cancer type and biomarkers help guide decisions.
• Side effects are different from chemotherapy and are often manageable when reported early.
• Asking questions and sharing your goals helps ensure treatment decisions reflect what matters most to you.

Authors/Reviewers: Dr. Vishal Patel, MD, Kristen Linney, RN, Patient perspective: Mike and Jodi

Sponsors and Partners: Melanoma Research Foundation, LUNGevity