What is Endometrial Cancer?

Endometrial Cancer

Endometrial cancer forms in the tissue lining the uterus, is one of the most common cancers in American women. It is sometimes called uterine cancer, but there are other cells in the uterus that can become cancerous, including muscle or myometrial cells. These become sarcomas, which are less common. Most endometrial cancers are adenocarcinomas, or cancers that start in cells that make mucus and other fluids.


Women who use estrogen without progesterone, especially for long periods of time, are at an increased risk for endometrial cancer. Women taking the drug tamoxifen to prevent or treat breast cancer also have an increased risk.

Obese women have higher levels of estrogen in their bodies, which also puts them at higher risk for this disease. Women who have had an inherited form of colorectal cancer have a higher risk of developing uterine cancer than other women.

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